MicroRNA miR-21 Attenuates Human Cytomegalovirus Replication in Neural Cells by Targeting Cdc25a
نویسندگان
چکیده
منابع مشابه
MicroRNA miR-21 attenuates human cytomegalovirus replication in neural cells by targeting Cdc25a.
UNLABELLED Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects, primarily manifesting as neurological disorders. HCMV infection alters expression of cellular microRNAs (miRs) and induces cell cycle arrest, which in turn modifies the cellular environment to favor virus replication. Previous observations found that HCMV infection reduces miR-21 expression in neur...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2015
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01740-14